Image-Guided Spine Procedures¶
Definition¶
Image-guided spine procedures encompass a range of diagnostic and therapeutic interventions performed under real-time imaging guidance — primarily fluoroscopy and CT — to precisely target spinal structures. These procedures include injections, biopsies, drainage, and ablation techniques used for pain management, diagnosis, and treatment of spinal pathology.
Guidance Modalities¶
Fluoroscopy¶
- Most commonly used for routine spine injections
- Real-time X-ray imaging allows needle positioning with contrast confirmation
- Advantages: widely available, fast, allows dynamic contrast injection to confirm needle position
- Limitations: limited soft tissue visualization; radiation exposure to patient and operator
CT Guidance¶
- Provides cross-sectional imaging for precise needle placement
- Advantages: superior anatomic detail; can target structures not accessible under fluoroscopy; confirms avoidance of critical structures
- Limitations: no real-time imaging (intermittent scans); higher radiation dose than fluoroscopy; more time-consuming
- CT fluoroscopy — near-real-time CT imaging; combines advantages of both
Ultrasound Guidance¶
- Increasingly used for superficial procedures (facet injections, sacroiliac joint injections)
- Advantages: no radiation; real-time imaging; portable
- Limitations: limited deep visualization; operator-dependent; not suitable for all spine procedures
Common Procedures¶
Epidural Steroid Injections (ESI)¶
| Approach | Technique | Target |
|---|---|---|
| Interlaminar | Needle between laminae into the epidural space | Central and bilateral radiculopathy; spinal stenosis |
| Transforaminal | Needle into the neural foramen along the exiting nerve root | Unilateral radiculopathy; foraminal stenosis |
| Caudal | Needle through the sacral hiatus into the caudal epidural space | Low lumbar/sacral radiculopathy; post-surgical patients |
Facet Joint Procedures¶
- Intra-articular facet injection — diagnostic and therapeutic injection of anesthetic and steroid into the facet joint
- Medial branch block (MBB) — anesthetic injection onto the medial branch of the dorsal ramus that innervates the facet joint; used for diagnosis
- Radiofrequency ablation (RFA) — thermal ablation of the medial branch nerve; performed after positive diagnostic MBBs; provides longer-lasting pain relief (6–12 months)
Sacroiliac Joint Injection¶
- Fluoroscopic or CT-guided injection into the SI joint
- Diagnostic (anesthetic) and therapeutic (steroid)
Vertebral Augmentation¶
- Vertebroplasty — injection of polymethylmethacrylate (PMMA) bone cement into a fractured vertebral body under fluoroscopic or CT guidance
- Kyphoplasty — a balloon is first inflated within the vertebral body to create a cavity and restore height before cement injection
- Indications: painful osteoporotic vertebral compression fractures refractory to conservative management
Percutaneous Biopsy¶
- CT-guided biopsy of vertebral body lesions, paravertebral masses, or disc space (for suspected infection)
- Core needle biopsy provides tissue for histopathologic and microbiologic analysis
- Coaxial technique allows multiple samples through a single access
Abscess Drainage¶
- CT-guided percutaneous drainage of paravertebral, psoas, or epidural abscesses
- Often combined with antibiotic therapy
- May be definitive treatment or a bridge to surgery
Clinical Pearl
Transforaminal epidural steroid injections carry a small but serious risk of spinal cord infarction due to inadvertent injection into a radiculomedullary artery (including the artery of Adamkiewicz). This risk is highest in the thoracic spine and at levels above L3. Digital subtraction angiography (DSA) before steroid injection can identify arterial uptake, and using non-particulate steroids (dexamethasone) instead of particulate steroids (triamcinolone, methylprednisolone) at high-risk levels reduces the risk of catastrophic embolic infarction.
Complications¶
- Infection — rare with proper sterile technique
- Bleeding — epidural hematoma (higher risk with anticoagulation)
- Nerve injury — from direct needle trauma or intraneuronal injection
- Dural puncture — headache; CSF leak
- Spinal cord infarction — rare but catastrophic; related to arterial injection
- Cement leakage — in vertebroplasty/kyphoplasty; can cause radiculopathy or embolism if severe
- Allergic reaction to contrast or medications
- Radiation exposure — to patient and operator
Key Points¶
- Fluoroscopy is the standard guidance modality for routine spine injections; CT provides superior anatomic detail for complex cases
- Epidural steroid injections are the most common image-guided spine procedure
- Facet joint diagnosis involves a stepwise approach: diagnostic MBB → confirmatory MBB → RFA
- Vertebral augmentation (vertebroplasty/kyphoplasty) treats painful compression fractures
- CT-guided biopsy is essential for tissue diagnosis of unknown vertebral lesions
- Non-particulate steroids should be used for transforaminal injections above L3 to minimize vascular risk
References¶
- Patel K, Chopra P, Martinez S, Upadhyayula S. Epidural Steroid Injections. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470189/
- Helm S II, Harmon PC, Noe C, Calodney AK, Abd-Elsayed A, Knezevic NN, Racz GB. Transforaminal Epidural Steroid Injections: A Systematic Review and Meta-Analysis of Efficacy and Safety. Pain Physician. 2021;24(S1):S209-S232. Available from: https://pubmed.ncbi.nlm.nih.gov/33492919/
- Cohen SP, Bhaskar A, Bhatia A, et al. Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group. Reg Anesth Pain Med. 2020;45(6):424-467. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7362874/
- Chandra RV, Maingard J, Asadi H, Slater LA, Mazwi TL, Marcia S, Barr J, Hirsch JA. Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data? AJNR Am J Neuroradiol. 2018;39(5):798-806. Available from: https://pubmed.ncbi.nlm.nih.gov/29170272/
- Wiesner EL, Hillen TJ, Long J, Jennings JW. Percutaneous CT-Guided Biopsies of the Cervical Spine: Technique, Histopathologic and Microbiologic Yield, and Safety at a Single Academic Institution. AJNR Am J Neuroradiol. 2018;39(5):981-985. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7410669/
- Transforaminal epidural steroid injection. Radiopaedia.org. Available from: https://radiopaedia.org/articles/transforaminal-epidural-steroid-injection